At H1, we believe access to the best healthcare information is a basic human right. Our mission is to provide a platform that can optimally inform every doctor interaction globally. This promotes health equity and builds needed trust in healthcare systems. To accomplish this our teams harness the power of data and AI-technology to unlock groundbreaking medical insights and convert those insights into action that result in optimal patient outcomes and accelerates an equitable and inclusive drug development lifecycle. Visit h1.co to learn more about us.

H1’s Customer Success team is focused on building deep, trusted relationships with existing customers to ensure they successfully implement the H1 platform, drive sustained engagement, and realize measurable business value from our solutions.

WHAT YOU'LL DO AT H1
The primary objective of the Principal Customer Success Manager is to serve as a strategic, trusted advisor to a portfolio of H1’s largest and most complex customers. You will own the customer relationship end-to-end, partnering closely with both senior client stakeholders and users to drive adoption, value realization, retention, and growth across either H1’s Clinical or Medical & Commercial product lines.

This role is designed for a highly autonomous, principal-level Customer Success leader who thrives in ambiguity, independently owns complex customer programs, strong personal accountability, and influences outcomes across customers, partners, and internal teams. Success in this role requires exceptional judgment, executive presence, and the ability to lead without direct authority.

You will:
- Own large-scale customer programs involving multiple business units, internal teams, System Integrators (SIs), and executive stakeholders.
- Lead cross-functional initiatives by establishing governance, driving accountability, managing dependencies, and ensuring successful execution across internal and external teams.
- Operate as the strategic point of contact for complex customer engagements, aligning competing priorities while driving measurable business outcomes and managing the overall account.
- Lead multiple concurrent, cross-functional customer programs, balancing competing priorities across customer executives, implementation partners, and internal stakeholders while maintaining alignment on strategic objectives.
- Build strong relationships with senior and executive-level stakeholders, positioning H1 as a critical partner in achieving their organizational goals.
- Operate with minimal oversight while independently prioritizing competing customer and business needs.
- Exercise sound judgment in highly ambiguous situations where there may not be an established playbook.
- Identify gaps, define solutions, and drive execution without requiring direction from leadership.
- Successfully navigate complex stakeholder dynamics during periods of organizational change or customer escalation.
- Own and drive account strategy, including implementation and adoption plans, success metrics, renewal readiness, and expansion opportunities.
- Lead regular executive business reviews, clearly articulating performance against KPIs, ROI, and strategic impact.
- Serve as the voice of the customer internally, providing structured feedback to product, engineering, and leadership teams to inform roadmap and prioritization.
- Collaborate cross-functionally with Product, Engineering, Sales, and Support to ensure a seamless customer experience across the full lifecycle.
- Consistently drive improvements in MAUs, NPS, CSAT, retention, and ARR across your book of business.
- Proactively identify and mitigate risk across all areas of the account.

ABOUT YOU
We’re looking for a Principal Customer Success Manager who is passionate about delivering measurable value to enterprise customers at scale. You bring a strategic mindset, strong executive presence, and the ability to balance deep problem-solving with long-term relationship management. You thrive in fast-paced environments and take pride in owning outcomes for your customers.
- You quickly establish credibility and require little ramp-up to begin managing strategic customer relationships in the Pharma & CRO space.
- You naturally create structure in ambiguous environments and enjoy solving complex organizational challenges.
- You have exceptional ownership and accountability, following through on commitments without requiring close oversight.
- You are known for bringing order to difficult customer situations and driving successful outcomes.
- You influence without authority and effectively lead cross-functional teams toward shared objectives.

REQUIREMENTS
- 5+ years of experience in Customer Success, Account Management, Consulting, Program Management, or equivalent strategic customer-facing experience within an Enterprise or Strategic B2B SaaS environment.
- Demonstrated experience owning complex, high-ARR accounts with senior stakeholder engagement.
- Strong project management experience across multi-threaded, high-priority initiatives.
- Experience working in or with Life Sciences organizations strongly preferred; Medical Affairs or Clinical experience is a plus.
- Proven ability to manage renewals, mitigate risk, and identify expansion opportunities.

COMPENSATION
This role pays $115,000 to $135,000 per year, based on experience, plus variable commission, based on performance, in addition to stock options.

Anticipated role close date: 09/07/2026

H1 OFFERS

- Full suite of health insurance options, in addition to generous paid time off

- Pre-planned company-wide wellness holidays

- Retirement options

- Health & charitable donation stipends

- Impactful Business Resource Groups

- Flexible work hours & the opportunity to work from anywhere

- The opportunity to work with leading biotech and life sciences companies in an innovative industry with a mission to improve healthcare around the globe

H1 is proud to be an equal opportunity employer that celebrates diversity and is committed to creating an inclusive workplace with equal opportunity for all applicants and teammates. Our goal is to recruit the most talented people from a diverse candidate pool regardless of race, color, ancestry, national origin, religion, disability, sex (including pregnancy), age, gender, gender identity, sexual orientation, marital status, veteran status, or any other characteristic protected by law.

H1 is committed to working with and providing access and reasonable accommodation to applicants with mental and/or physical disabilities. If you require an accommodation, please reach out to your recruiter once you've begun the interview process. All requests for accommodations are treated discreetly and confidentially, as practical and permitted by law.

H1

Latest Jobs

Principal Customer Success Manager - Pharma